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Dunfeng Du Selected Research

5- (3- (4- (4- benzylpiperazin- 1- yl)- N- (4- phenylthiazol- 2- yl))propanamide

2/2022TJ-M2010-5, A self-developed MyD88 inhibitor, attenuates liver fibrosis by inhibiting the NF-κB pathway.
8/2020TJ-M2010-5, a novel MyD88 inhibitor, corrects R848-induced lupus-like immune disorders of B cells in vitro.
2/2019Short-term use of MyD88 inhibitor TJ-M2010-5 prevents d-galactosamine/lipopolysaccharide-induced acute liver injury in mice.

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Dunfeng Du Research Topics

Disease

2Inflammation (Inflammations)
08/2020 - 02/2019
2Delayed Graft Function
11/2019 - 01/2014
1Fibrosis (Cirrhosis)
02/2022
1Liver Cirrhosis (Hepatic Cirrhosis)
02/2022
1COVID-19
12/2021
1Respiratory Insufficiency (Respiratory Failure)
12/2021
1Infections
12/2021
1Multiple Organ Failure (MODS)
12/2021
1Kidney Calculi (Kidney Stone)
12/2021
1Urinary Bladder Calculi (Bladder Calculi)
12/2021
1Cardiac Arrhythmias (Arrythmia)
01/2021
1Atrial Fibrillation
01/2021
1Chronic Kidney Failure (Chronic Renal Failure)
12/2020
1Primary hyperoxaluria type 1
12/2020
1Immune System Diseases (Immune Disorders)
08/2020
1Abdominal Aortic Aneurysm
02/2020
1Cardiovascular Diseases (Cardiovascular Disease)
02/2020
1Solitary Kidney
11/2019
1Primary Hyperoxaluria (Oxaluria, Primary)
07/2019
1Hyperoxaluria (Oxaluria)
07/2019
1Body Weight (Weight, Body)
02/2019
1Reperfusion Injury
01/2014

Drug/Important Bio-Agent (IBA)

35- (3- (4- (4- benzylpiperazin- 1- yl)- N- (4- phenylthiazol- 2- yl))propanamideIBA
02/2022 - 02/2019
1Toll-Like Receptors (Toll-Like Receptor)IBA
02/2022
1Carbon Tetrachloride (Tetrachloromethane)IBA
02/2022
1Interleukin-2 (IL2)IBA
01/2021
1Vitamin B 6IBA
12/2020
1AutoantibodiesIBA
08/2020
14,4',4''- (4- propyl- ((1)H)- pyrazole- 1,3,5- triyl) tris-phenolIBA
02/2020
1Estrogens (Estrogen)FDA Link
02/2020
12,3-bis(4-hydroxyphenyl)-propionitrileIBA
02/2020
1Fulvestrant (Faslodex)FDA Link
02/2020
1NAD (NADH)IBA
02/2020
1Messenger RNA (mRNA)IBA
02/2020
1Estradiol (Delestrogen)FDA LinkGeneric
02/2020
1Calcium OxalateIBA
07/2019
1OxalatesIBA
07/2019
1Biomarkers (Surrogate Marker)IBA
07/2019
1Alanine-glyoxylate transaminase (alanine-glyoxylate aminotransferase)IBA
07/2019
1MicroRNAs (MicroRNA)IBA
07/2019

Therapy/Procedure

3Kidney Transplantation
12/2021 - 01/2014
1Lithotripsy (Extracorporeal Shockwave Lithotripsy)
12/2021
1Transplantation
11/2019
1Intraperitoneal Injections
02/2019